@article{7435,
  author = {X. Chen and M. Tirado and J. D. Steill and J. Oomens and N. C. Polfer},
  title = {Cyclic peptide as reference system for b ion structural analysis in the gas phase},
  abstract = {Infrared multiple photon dissociation spectroscopy and hydrogen/deuterium exchange methods are used to confirm the macrocylic structure of a b(6) peptide fragment by direct comparison with a synthetically made cyclic peptide. The acetylation of the peptide N-terminus results in the inhibition of the macrocyclic formation, supporting the "head-to-tail" cyclization mechanism. Differences in hydrogen/deuterium exchange rates for macrocyclic and oxazalone structure peptide fragments are interpreted to be a result of the complex interplay of multiple basic sites in the peptide fragment, supporting the relay mechanism for deuterium exchange with CH(3)OD. Copyright (C) 2011 John Wiley & Sons, Ltd.},
  year = {2011},
  journal = {Journal of Mass Spectrometry},
  volume = {46},
  pages = {1011-1015},
  month = {Oct},
  isbn = {1076-5174},
  doi = {10.1002/jms.1982 },
  language = {English},
}