DIFFER
DIFFER EVENT

Plasmon-enhanced single-molecule detection

Optical detection of single molecules is widely used in fields ranging from biology to materials science. The ability to detect single molecules has long relied on fluorescence approaches due to their high signal-to-background ratio. This limits the applicability of the approach to fluorescently labelled molecules with a high quantum yield. I will describe how weakly and completely non-fluorescent molecules can be detected by exploiting single plasmonic particles. I will particularly discuss two applications, namely single-molecule biosensing and the plasmon-enhanced detection of catalytic activity of enzymes.

Date
-
Location
seminar room
Speaker
Peter Zijlstra
Affiliation
TU/e

Go to the Events page.